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Overview of Courses

Courses by Quarter

Summer   Fall   Winter   Spring

Courses by Topic



With the exception of the Master's and ATCR Seminars and Epi 212, all courses are open to individuals both within and outside the UCSF community. Those not in the ATCR or Master's programs pay fees which can also be found in the course applications.

Courses Offered in Online Format

Summer

*Course is also offered in online format

*Designing Clinical Research (EPI 150.03 and EPI 202)
These courses provide instruction in developing a clinical research question and creating a concise protocol that includes literature review, study design, subject sampling and recruitment, instruments and other measurement approaches, sample size, consent form, budget and timetable. Each trainee reviews and supports the work of colleagues. The course closely follows the textbook Designing Clinical Research, by S. Hulley and other TICR faculty, now in its third edition. EPI 150.03 is intended for undergraduate and professional students as well as clinical residents. EPI 202 is intended for doctoral students, fellows, or faculty members.

Building a Career in Clinical Research (EPI 227)
Trainees learn the nuts and bolts of working in a clinical research environment, including choosing a mentor, managing time, writing papers, obtaining grants, and getting promoted. Scholars also receive a broad introduction to different types of clinical research careers from leaders in academia, public health, government, non-profit foundations and the biotechnology industry. Trainees prepare a curriculum vitae in University of California format and develop a detailed career plan to review with their mentors.

*Database Management Systems for Clinical Research (EPI 218)
Instruction in choosing the appropriate data management system; design of research databases; options in data entry; form and report generation; computer security; and budgeting for data management personnel and equipment.

*Introduction to Statistical Computing in Clinical Research (BIOSTAT 212)
Instruction in use of statistical software for exploring and analyzing clinical research data. While the roles of spreadsheet and relational database programs will be discussed, the course will focus on the STATA statisical software package for analyzing and presenting data.

Fall
* Course is also offered in online format

*Epidemiologic Methods (EPI 203)
Instruction in the diverse array of study designs, and their theoretical interrelatedness, available in clinical and epidemiologic research; importance of measurement; different types of measures of disease occurrence; methods to measure exposure - disease association; measures of attributable risk; effect-measure modification; approaches to identify and minimize selection, measurement and confounding bias; and conceptual motivation for more sophisticated methods (e.g., regression or marginal structural approaches) to manage confounding, which are increasingly common tools in epidemiologic analyses.

*Clinical Epidemiology (EPI 204)
Instruction in the research implications of evidence-based clinical medicine, including the specifications of diagnostic tests, screening tests, and prognostic tests.

*Biostatistical Methods for Clinical Research I (BIOSTAT 200)
Introduction to descriptive statistics, distributions, probabability, exploratory data analysis, and selected variable parametric and non-parametric inference. The STATA software package will be used throughout to implement concepts learned in class and to allow scholars to begin to explore their own data.

Biostatistical Methods for Clinical Research IV (BIOSTAT 210)
A continuation in the biostatistics for clinical research sequence, covering advanced methods for building and evaluating regression models. The emphasis is on methods which cut across common families of regression models in biostatistics: predictor selection, model diagnostics, and missing data. The statistics package STATA will be used throughout the course.

Program Evaluation in Clinical and Public Health Settings (EPI 242)
Instruction in different types of program evaluation, including needs assessment, formative research, process evaluation, monitoring of outputs and outcomes and impact assessment; developing an evaluation plan and using systematically collected information about a program to understand whether and how the program is meeting its stated goals and objectives; improve program effectiveness; make decisions about future programming.

Translating Evidence Into Practice: Individual-Centered Implementation Strategies (EPI 246)
Instruction in developing interventions for individual health behavior change, including behavior change strategies at the individual, interpersonal, and system/community level; developing practical frameworks to integrate principles of behavior change theory.

Environmental and Occupational Epidemiology (EPI 256)
Using landmark case studies of environmental or occupational disasters, current concepts and issues in the field of environmental and occupational epidemiology are addressed, including the determination of causality, risk assessment, cluster investigations, active and passive surveillance, monitoring, biomarkers, and health risk communication.

Infectious Disease Epidemiology (EPI253)
Review of intermediate and advanced concepts in infectious disease epidemiology, using examples from the contemporary literature. Topics include social network analysis, vaccine efficacy, epidemic dynamics, evaluation of communicable disease interventions, surveying hard-to-reach populations, prophylaxis and mass drug administration.

Grant Writing Workshop on Mentored Career Development Awards
Instruction in writing successful grant applications for NIH mentored career development awards. Workshop uses examples from patient-oriented research career development awards (K23s). Underlying concepts for the career development plan, mentoring plan, and research plan also apply to research scientist development awards (K01s) and clinical scientist development awards (K08s).

Masters Seminar I (EPI 220)
The seminar provides a forum for presenting scholar's projects, and for evaluating controversies in clinical research.

Masters Seminar II Fall (EPI 221)
The seminar provides a forum for scholars to present their projects and specialized methodologic topics.

ATCR Seminar (EPI 230)
These monthly seminars provide a support group for discussing the design or conduct of trainees' studies and for critique of contemporary clinical research literature.

Winter

* Course is also offered in online format

Clinical Trials (EPI 205)
Instruction in experimental design options; methods of randomization; blinding, interventions and controls; measuring outcomes and adverse effects; follow-up, compliance and postrandomization problems; ethical issues; and working with pharmaceutical companies.

Biostatistical Methods for Clinical Research II (BIOSTAT 208)
Instruction in multiple predictor analyses as a tool for control of confounding and for constructing predictive models. Topics will include linear regression and logistic regression. The STATA statistical package will be used throughout.

Statistical Issues in Design, Monitoring, and Analysis of Randomized Controlled Trials (BIOSTAT 226)
Instruction in advanced topics in biostatistics in two subject areas: 1) issues in the design and analysis of randomized clinical trials; and 2) bioinformatics.

Decision and Cost Effectiveness Analysis in Medicine (EPI 213)
Instruction in creating decision trees and other analytic models; obtaining appropriate probabilities, utilities and costs; and completing analyses using customized software.

Molecular and Genetic Epidemiology I (EPI 217)
Introduction to the concepts, principles, and use of molecular and genetic methods in epidemiologic and clinical research and how to develop a framework for interpreting, assessing, and incorporating molecular and genetic measures in research.

Medical Informatics (EPI 206)
Instruction in the core concepts of medical informatics: vocabularies, interchange standards, decision support systems, and how computers are used to manage information in health care and to support clinical research.

Qualitative Research Methods (EPI 240)
Introduces basic qualitative research methods used in clinical settings: question design and interviewing techniques; focus group analysis; ethnographic fieldwork, notes and narrative analysis; and audio and video data collection and analysis.

Translating Evidence Into Practice: System-Centered Implementation Strategies (EPI 247)
Instruction in translational tools at health care system level to promote the adoption of evidence-based medicine by the public and providers through mechanisms that influence health care delivery systems.

Translating Evidence Into Policy: Framing Research to Influence Policy (EPI 249)
Instruction in types of questions that can be addressed with large administrative and clinical databases; gaining access to these databases; determining validity of information; risk adjustment; linking datasets; and building registries. Instruction in the policy process and strategies for collecting and disseminating research findings to inform and influence that process. The course will be taught through a series of lectures and interactive sessions during which trainees will have an opportunity to apply the strategies to their own work.

Epidemiologic Methods II (EPI 207)
Topics will include: the interrelationships between various measures of disease occurrence and association; concepts of attributable risk; interactions; practical and theoretical considerations of the most common study designs in observational research; methods of reducing confounding including matching, instrumental variables and propensity scores.

Epidemiology of Aging (EPI 210)
Instruction in the issues and methods for the study of the epidemiology of aging with a focus on common chronic diseases in older populations.

F, K, R Grant Writing Workshop (EPI 258)
This course is designed to provide doctoral students, post-doctoral fellows and early investigators with training on the preparation of an NIH F, K or R series grant application.

Neglected Tropical Diseases (EPI 261)
This seminar course will provide an overview of neglected tropical diseases (NTDs), especially those transmitted by vectors (arthropods, snails), their public health importance and strategies for their control.

Pharmaceopidemiology (EPI 262)
This seminar course will provide an overview of methods, data sources, and other selected topics in pharmacoepidemiology.

Grant Writing Workshop on Mentored Career Development Awards
Instruction in writing successful grant applications for NIH mentored career development awards. Workshop uses examples from patient-oriented research career development awards (K23s). Underlying concepts for the career development plan, mentoring plan, and research plan also apply to research scientist development awards (K01s) and clinical scientist development awards (K08s).

Masters Seminar I (EPI 220)
The seminar provides a forum for presenting scholar's projects, and for evaluating controversies in clinical research.

Masters Seminar II Winter (EPI 221)
The seminar provides a forum for scholars to present their projects and specialized methodologic topics.

ATCR Seminar (EPI 230)
These monthly seminars provide a support group for discussing the design or conduct of trainees' studies and for critique of contemporary clinical research literature.

Spring
* Course is also offered in online format

Biostatistical Methods for Clinical Research III (BIOSTAT 209)
A continuation of the Winter Quarter course in multivariable statistical analysis that includes instruction in survival analysis and analysis of repeated measures and clustered data. The course culminates with student presentations of statistical analyses of their own research projects.

Systematic Reviews (EPI 214)
Instruction in the methods of systematic and unbiased identification of primary research studies; abstraction of data; determination of summary estimates and evaluation of heterogeneity.

Publishing and Presenting Research (EPI 212)
Instruction in preparing abstracts, posters, all aspects of manuscripts, and oral presentations; instruction in oral presentations includes videotaping and critique of trainees' presentations.

Statistical Methods in Genetic Epidemiology (BIOSTAT 219)
Instruction in selected statistical aspects of population-based and family-based candidate gene association studies, quantitative trait mapping in model organisms, and methods for dealing with multiple comparisons.

Health Disparities Research Methods (EPI 222)
Instruction in the meaning of race, ethnicity, social class, and culture, and how these constructs affect the conduct and interpretation of clinical research.

Translating Evidence Into Practice: Theory and Design (EPI 245)
An introduction to the different target audiences and approaches needed to translate biomedical evidence into practice. The course is the gateway for scholars who plan for additional study within this discipline but also suffices as cross-exposure for scholars from other disciplines. In addition to didactic work, scholars are guided through the creation of a research protocol aimed towards translating their particular choice of evidence into practice.

Translating Practice into Evidence: Community Engaged Research (EPI 248)
Introduces the principles and applied methods of community engaged research, including defining the community and partnership models for identifying relevant research questions, developing and implementing study designs, interpreting and disseminating findings, and scaling-up studies for translational implementation research.

Development and Approval of Drugs and Devices (EPI 260)
Instruction in drug and device development from late preclinical through phase 3 clinical studies; will introduce students to drug/device regulations, investigational new drug filings, assessment of drug candidates, statistics, safety monitoring, clinical study design and conduct.

Advanced Approaches to the Analysis of Observational Data (BIOSTAT 215)
A common goal of observational clinical or epidemiologic research is to estimate the causal effect of particular exposures or interventions on some health outcome. This course will describe more advanced methods that may succeed in estimating causal effects in cases where standard approaches break down.

Cancer Epidemiology (EPI 252)
This course will cover the basic understanding of the principles and methods of epidemiology, and the application of this knowledge to the study of the epidemiology of neoplastic diseases. 

Research Methods in Chronic Disease Epidemiology (EPI 265)
This course will focus on clearly articulating and testing research hypotheses related to the determinants and consequences of chronic conditions. Each session will introduce specific methodological concepts for epidemiologic studies, organized around an illustrative applied research paper. The course will emphasize causal inference from observational data. Most examples will be drawn from literature on social and lifecourse determinants of dementia, stroke, and cardiometabolic disease.

Social Epidemiology: Methods, Measures, and Concepts (EPI 254)
This course will review the theoretical and methodological underpinnings of social epidemiology. The course will cover theoretical considerations for social epidemiology, frameworks on social determinants of health, and examine how the social environment and context interacts with and influences etiology of diseases.

Social Epidemiology: Concepts and Measures for Studying Social Factors and Health (EPI 255)
This course will cover the research in the key topics in social epidemiology: race/ethnicity (including racism), social class, income distribution/inequality, and neighborhood and place. Students will read selected articles, learn core concepts and methods, and discuss findings, limitations, and research opportunities.

Research Methods in Chronic Disease Epidemiology (EPI 265)
This course will focus on clearly articulating and testing research hypotheses related to the determinants and consequences of chronic conditions. Each session will introduce specific methodological concepts for epidemiologic studies, organized around an illustrative applied research paper. The course will emphasize causal inference from observational data. Most examples will be drawn from literature on social and lifecourse determinants of dementia, stroke, and cardiometabolic disease.

Advanced F, K, R Grantwriting Workshop (EPI 259)
This is an advanced course on grant preparation. The objective of this course is to refine F, K, R applications so that they are submission ready.  Students complete all final remaining grant components, identify the appropriate study section, finalize their formatting and proof all grant components.  Submission tips and guidance are provided to ensure timely submissions.

Grant Writing Workshop on Mentored Career Development Awards
Instruction in writing successful grant applications for NIH mentored career development awards. Workshop uses examples from patient-oriented research career development awards (K23s). Underlying concepts for the career development plan, mentoring plan, and research plan also apply to research scientist development awards (K01s) and clinical scientist development awards (K08s).

Masters Seminar I (EPI 220)
The seminar provides a forum for presenting scholar's projects, and for evaluating controversies in clinical research.

Masters Seminar II Spring (EPI 221)
The seminar provides a forum for scholars to present their projects and specialized methodologic topics.

ATCR Seminar (EPI 230)
These monthly seminars provide a support group for discussing the design or conduct of trainees' studies and for critique of contemporary clinical research literature.