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Introduction to Statistical Computing in Clinical Research
Biostat 212 Summer 2008 (1 unit)




OBJECTIVES

NOTE: This course is on Thursday afternoons at China Basin.

Performing clinical research in the current era requires the use of computers, and the clinical research curriculum at UCSF therefore requires a high level of competency in the use of database, spreadsheet, and statistical software programs. This course is designed to introduce you to these programs, prepare you for subsequent courses in the clinical research curriculum, and teach you the skills you will need to start analyzing your own clinical research data.

The specific objectives of this course are to provide you with an introduction to:
1. The roles of spreadsheet, relational database and statistical software packages such as STATA in analyzing clinical research data;
2. Using STATA for importing, cleaning, managing, describing and analyzing clinical research data;
3. Applying concepts from other TICR courses using STATA and Excel; and
4. Applying these skills to analyzing data from your own research project.

PREREQUISITES

Designing Clinical Research (Epi 202, may be taken concurrently) and possession of a MD, PhD, DDS or PharmD or equivalent doctoral degree. Exceptions to these prerequisites may be made with the consent of the Course Director, space permitting.

FACULTY

Course Director:

Mark J. Pletcher, MD MPH
Campus Phone: 415-514-8008
email: mpletcher@epi.ucsf.edu

Lecturer:

Andy Choi, MD MAS
email: Andy.Choi@va.gov

Computer Lab Instructors:

Carolyn Calfee, MD
email: carolyn.calfee@ucsf.edu

 

Mandana Khalili, MD MAS
email: mandana.khalili@ucsf.edu

 

Barbara Grimes, PhD
email: BGrimes@psg.ucsf.edu

Teaching Assistants:

Phil Blumenshine, MSc
email: BlumenshineP@fcm.ucsf.edu

Jen Cocohoba, PharmD
email: cocohobaj@pharmacy.ucsf.edu


FORMAT

This course will be taught on seven consecutive Thursday afternoons during the summer (7/31-9/11) at China Basin. Lectures are Thursday from 1:15-2:45. Labs follow each lecture, staffed from 3:00-4:00.

SOFTWARE AND TEXTBOOKS

Required: STATA 10 (or earlier version)

The statistical software package Stata (Stata Corporation, College Station, Texas) is used in the program. This software package is required for the course. We strongly recommend that you purchase a personal copy of this program and bring a laptop to all Lab sessions in China Basin. Along with wireless Internet access, the computer lab at China Basin has a very limited number of computer terminals that may be used during labs. You can also get access to STATA in the library computers at Parnassus (with a GALEN password). The lab sessions will be much less useful, however, if you cannot actually work on the assignments during the lab, so make every effort to bring your laptop with Stata loaded. We recommend Stata/SE version 10, but other versions are acceptable for the class.

Microsoft Excel (Microsoft, Redmund, WA), which is widely available (including on all UCSF library computers and China Basin terminals), will also be used in the course.

Optional: The following three books can be ordered from Stata.com at stata.com/bookstore, and will also be placed on reserve at the UCSF Library:

Getting Started with Stata (GSS) - This manual comes with your purchase of STATA if you get the Base Stata Documentation Set.

A Visual Guide to Stata Graphics (VGSG) - Useful reference for creating figures.

An Introduction to Stata for Health Researchers (ISHR) - Nice overview and instruction on many basic topics.

ASSIGNMENTS AND GRADING

Assignments-Grades will be based on the Lab assignments and the Final Project. Lab assignments will be due by the start of lecture the following week, and should be emailed to the course email address at either Biostat212_section1@yahoo.com or Biostat212_section2@yahoo.com. Labs turned in <1 week late will receive half credit; after that, no points will be awarded. The Final Project, a Table and Figure created from your own data, will count for about half of the roughly 320 total points possible for the course, and will be due on 9/18/08.

Grading is Satisfactory/Unsatisfactory-Students must hand in all six labs (even if late), must complete a satisfactory Final Project, and must receive at least 80% of the total number of points assigned during the quarter to receive a “Satisfactory” grade.

ENROLLMENT

This course is open to a limited number of individuals outside of the ATCR and Master's programs. Preference is given to UCSF-affiliated personnel. We regret that auditing is not permitted. To enroll in this course please fill out and submit the application below. Cost and submission information are in the application.

Application (Word doc, 20KB)